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Defining clear study objectives and endpoints is the foundation of a successful clinical trial. Each study objective should be paired with one or more endpoints that effectively measure the outcomes of interest. However, the selection of objectives and endpoints to answer the research questions of the study effectively can be an intricate and time-consuming process. Emtex Statisticians can offer support by facilitating discussions to clarify study objectives and identify relevant endpoints as well as by ensuring that objectives and endpoints are aligned with the research aims.